8OEE
Crystal structure of human AQP2 T126M mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aquaporin-2 | polymer | 241 | 25169.3 | 4 | UniProt (P41181) Pfam (PF00230) | Homo sapiens (human) | AQP-2,ADH water channel,Aquaporin-CD,AQP-CD,Collecting duct water channel protein,WCH-CD,Water channel protein for renal collecting duct |
| 2 | E, F (D) | CADMIUM ION | non-polymer | 112.4 | 2 | Chemie (CD) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 241 (UniProt: P41181)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Met 126 | Thr 126 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100677.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 224.8 | |
| All* | Total formula weight | 100902.1 |
