8ODO

Structure of human guanylylated RTCB in complex with Archease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	RNA-splicing ligase RtcB homolog	polymer	507	55412.3	4	UniProt (Q9Y3I0) Pfam (PF01139) In PDB	Homo sapiens (human)	3'-phosphate/5'-hydroxy nucleic acid ligase
2	B, D, F, H	Protein archease	polymer	200	22997.7	4	UniProt (A8K0B5) Pfam (PF01951) In PDB	Homo sapiens (human)
3	A, C, E, G	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	4	Chemie (5GP)
4	A, B, C, D, E...	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
5	A, C, E, G	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
6		water	water		18.0	643	Chemie (HOH)

Sequence modifications

A, C, E, G: 1 - 505 (UniProt: Q9Y3I0)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag

B, D, F, H: 1 - 179 (UniProt: A8K0B5)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	313639.9
Non-Polymers*	Number of molecules	16
	Total formula weight	2272.3
All*	Total formula weight	315912.2

*Water molecules are not included.