8KHU
Hepatitis B virus core protein Y132A mutant in complex with THPP derivatives 48
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Capsid protein | polymer | 155 | 17486.9 | 7 | UniProt (P03147) Pfam (PF00906) | Hepatitis B virus adw/991 | Core antigen,Core protein,HBcAg,p21.5 |
| 2 | H, I, K, M, O... (A, B, C, D, E) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 7 | Chemie (IPA) | |||
| 3 | J, L, N, P, S... (A, B, C, D, E...) | (6~{S},7~{R})-6,7-dimethyl-3-(2-oxidanylidenepyrrolidin-1-yl)-~{N}-[3,4,5-tris(fluoranyl)phenyl]-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-5-carboxamide | non-polymer | 407.4 | 6 | Chemie (VX0) | |||
| 4 | U (F) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | AA, BA, V, W, X... (F, G, A, B, C...) | water | water | 18.0 | 301 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G: 1 - 149 (UniProt: P03147)
| PDB | External Database | Details |
|---|---|---|
| Ala 132 | Tyr 132 | engineered mutation |
| Glu 150 | - | expression tag |
| Asn 151 | - | expression tag |
| Leu 152 | - | expression tag |
| Tyr 153 | - | expression tag |
| Phe 154 | - | expression tag |
| Gln 155 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 122408.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2957.1 | |
| All* | Total formula weight | 125365.5 |
