8K9I

Structure of CUL3-RBX1-KLHL22 complex without CUL3 NA motif

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	Cullin-3	polymer	752	87432.3	1	UniProt (Q13618) Pfam (PF00888) Pfam (PF10557) In PDB	Homo sapiens (human)
2	K, L	Kelch-like protein 22	polymer	178	20365.3	2	UniProt (Q53GT1) Pfam (PF00651) In PDB	Homo sapiens (human)
3	R	E3 ubiquitin-protein ligase RBX1, N-terminally processed	polymer	108	12290.0	1	UniProt (P62877) Pfam (PF12678) In PDB	Homo sapiens (human)	E3 ubiquitin-protein transferase RBX1,N-terminally processed

Sequence modifications

C: 25 - 768 (UniProt: Q13618)

PDB	External Database	Details
Lys 769	-	expression tag
Leu 770	-	expression tag
His 771	-	expression tag
His 772	-	expression tag
His 773	-	expression tag
His 774	-	expression tag
His 775	-	expression tag
His 776	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	140453.0
All*	Total formula weight	140453.0

*Water molecules are not included.