8JPE
Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (Q) | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 353 | 41282.9 | 1 | UniProt (P50148) Pfam (PF00503) | Homo sapiens (human) | Guanine nucleotide-binding protein alpha-q |
| 2 | B (Q) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | C (Q) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (Q) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) |
Sequence modifications
Q: 37 - 359 (UniProt: P50148)
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | initiating methionine |
| Gly 8 | - | expression tag |
| Cys 9 | - | expression tag |
| Thr 10 | - | expression tag |
| Leu 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Ala 13 | - | expression tag |
| Glu 14 | - | expression tag |
| Asp 15 | - | expression tag |
| Lys 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Ala 18 | - | expression tag |
| Val 19 | - | expression tag |
| Glu 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Lys 23 | - | expression tag |
| Met 24 | - | expression tag |
| Ile 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Arg 27 | - | expression tag |
| Asn 28 | - | expression tag |
| Leu 29 | - | expression tag |
| Arg 30 | - | expression tag |
| Glu 31 | - | expression tag |
| Asp 32 | - | expression tag |
| Gly 33 | - | expression tag |
| Glu 34 | - | expression tag |
| Arg 35 | - | expression tag |
| Ser 36 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41282.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 570.5 | |
| All* | Total formula weight | 41853.4 |
