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8JPE

Focused refinement structure of Galpha(q) in NTSR1-GRK2-Galpha(q) complexes

Functional Information from GO Data
ChainGOidnamespacecontents
Q0000166molecular_functionnucleotide binding
Q0001664molecular_functionG protein-coupled receptor binding
Q0001750cellular_componentphotoreceptor outer segment
Q0003924molecular_functionGTPase activity
Q0003925molecular_functionG protein activity
Q0005096molecular_functionGTPase activator activity
Q0005515molecular_functionprotein binding
Q0005525molecular_functionGTP binding
Q0005634cellular_componentnucleus
Q0005737cellular_componentcytoplasm
Q0005765cellular_componentlysosomal membrane
Q0005794cellular_componentGolgi apparatus
Q0005834cellular_componentheterotrimeric G-protein complex
Q0005886cellular_componentplasma membrane
Q0007165biological_processsignal transduction
Q0007186biological_processG protein-coupled receptor signaling pathway
Q0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Q0007200biological_processphospholipase C-activating G protein-coupled receptor signaling pathway
Q0007206biological_processphospholipase C-activating G protein-coupled glutamate receptor signaling pathway
Q0007208biological_processphospholipase C-activating serotonin receptor signaling pathway
Q0007213biological_processG protein-coupled acetylcholine receptor signaling pathway
Q0007215biological_processglutamate receptor signaling pathway
Q0007218biological_processneuropeptide signaling pathway
Q0007596biological_processblood coagulation
Q0007603biological_processphototransduction, visible light
Q0009649biological_processentrainment of circadian clock
Q0009755biological_processhormone-mediated signaling pathway
Q0010543biological_processregulation of platelet activation
Q0016020cellular_componentmembrane
Q0016787molecular_functionhydrolase activity
Q0019001molecular_functionguanyl nucleotide binding
Q0030234molecular_functionenzyme regulator activity
Q0031683molecular_functionG-protein beta/gamma-subunit complex binding
Q0031965cellular_componentnuclear membrane
Q0034695biological_processresponse to prostaglandin E
Q0046872molecular_functionmetal ion binding
Q0050821biological_processprotein stabilization
Q0060828biological_processregulation of canonical Wnt signaling pathway
Q0070062cellular_componentextracellular exosome
Q0071468biological_processcellular response to acidic pH
Q0099524cellular_componentpostsynaptic cytosol
Q0140582biological_processadenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P21279
ChainResidueDetails
QSER50
QTHR186
QASN274
QLYS275
QASP277
QALA331
QGLY51
QLYS52
QSER53
QTHR54
QSER156
QLEU180
QARG181
QARG183

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Deamidated glutamine; by Photorhabdus PAU_02230 => ECO:0000269|PubMed:24141704
ChainResidueDetails
QGLN209

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PDB entries from 2025-06-11

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