8JPD
Focused refinement structure of GRK2 in NTSR1-GRK2-Galpha(q) complexes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | Beta-adrenergic receptor kinase 1 | polymer | 688 | 79644.7 | 1 | UniProt (P21146) Pfam (PF00615) Pfam (PF00069) Pfam (PF00169) | Bos taurus (cattle) | Beta-ARK-1,G-protein-coupled receptor kinase 2 |
| 2 | B (G) | STAUROSPORINE | non-polymer | 466.5 | 1 | Chemie (STU) |
Sequence modifications
G: 2 - 689 (UniProt: P21146)
| PDB | External Database | Details |
|---|---|---|
| Pro 292 | Ala 292 | engineered mutation |
| Ile 295 | Arg 295 | engineered mutation |
| Asp 455 | Ser 455 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 79644.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 466.5 | |
| All* | Total formula weight | 80111.3 |
