8JNA

CRAF ras-binding domain chimera, apo form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B	RAF proto-oncogene serine/threonine-protein kinase, CRaf	polymer	94	10517.0	1	UniProt (P04049) UniProt (P15056) Pfam (PF02196) In PDB	Homo sapiens (human)	Proto-oncogene c-RAF,cRaf,Raf-1,Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1
2		water	water		18.0	30	Chemie (HOH)

Sequence modifications

B: 50 - 101 (UniProt: P04049)

PDB	External Database	Details
Gly 45	-	expression tag
Pro 46	-	expression tag
Leu 47	-	expression tag
Gly 48	-	expression tag
Ser 49	-	expression tag
Ser 65	Lys 65	engineered mutation
Tyr 99	Phe 99	engineered mutation

B: 102 - 113 (UniProt: P15056)
B: 114 - 141 (UniProt: P04049)

PDB	External Database	Details
Trp 120	Ser 120	engineered mutation
Glu 129	Asp 129	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	10517.0
All*	Total formula weight	10517.0

*Water molecules are not included.