8JI8
Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | TK receptor | polymer | 680 | 79313.2 | 4 | UniProt (Q16G28) Pfam (PF03722) Pfam (PF00372) Pfam (PF03723) In PDB | Aedes aegypti (yellow fever mosquito) | Prophenoloxidase 6 |
| 2 | D, A, B, C | COPPER (II) ION | non-polymer | 63.5 | 8 | Chemie (CU) | |||
| 3 | C, D, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 19 | Chemie (EDO) | |||
| 4 | C, A, B | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 3 | Chemie (TRS) | |||
| 5 | water | water | 18.0 | 774 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 680 (UniProt: Q16G28)
| PDB | External Database | Details |
|---|---|---|
| Gly 215 | Phe 215 | engineered mutation |
| Asp 216 | Glu 216 | engineered mutation |
| Gly 217 | Ala 217 | engineered mutation |
| Pro 218 | Ser 218 | engineered mutation |
| Asp 219 | Asn 219 | engineered mutation |
| Ser 220 | Arg 220 | engineered mutation |
| Val 221 | Ala 221 | engineered mutation |
| Val 222 | Ile 222 | engineered mutation |
| Arg 223 | Val 223 | engineered mutation |
| - | Asp 224 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 317252.8 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 2054.1 | |
| All* | Total formula weight | 319306.8 |
