8JI8

Crystal Structure of Prophenoloxidase PPO6 chimeric mutant (F215EASNRAIVD224 to G215DGPDSVVR223) from Aedes aegypti

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004097	molecular_function	catechol oxidase activity
A	0004497	molecular_function	monooxygenase activity
A	0004503	molecular_function	tyrosinase activity
A	0005576	cellular_component	extracellular region
A	0016491	molecular_function	oxidoreductase activity
A	0035011	biological_process	melanotic encapsulation of foreign target
A	0042417	biological_process	dopamine metabolic process
A	0042438	biological_process	melanin biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004097	molecular_function	catechol oxidase activity
B	0004497	molecular_function	monooxygenase activity
B	0004503	molecular_function	tyrosinase activity
B	0005576	cellular_component	extracellular region
B	0016491	molecular_function	oxidoreductase activity
B	0035011	biological_process	melanotic encapsulation of foreign target
B	0042417	biological_process	dopamine metabolic process
B	0042438	biological_process	melanin biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0004097	molecular_function	catechol oxidase activity
C	0004497	molecular_function	monooxygenase activity
C	0004503	molecular_function	tyrosinase activity
C	0005576	cellular_component	extracellular region
C	0016491	molecular_function	oxidoreductase activity
C	0035011	biological_process	melanotic encapsulation of foreign target
C	0042417	biological_process	dopamine metabolic process
C	0042438	biological_process	melanin biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0004097	molecular_function	catechol oxidase activity
D	0004497	molecular_function	monooxygenase activity
D	0004503	molecular_function	tyrosinase activity
D	0005576	cellular_component	extracellular region
D	0016491	molecular_function	oxidoreductase activity
D	0035011	biological_process	melanotic encapsulation of foreign target
D	0042417	biological_process	dopamine metabolic process
D	0042438	biological_process	melanin biosynthetic process
D	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00209
Number of Residues	20
Details	HEMOCYANIN_1 Arthropod hemocyanins / insect LSPs signature 1. YFrEDIgvNlhhwhwHlvyP

Chain	Residue	Details
A	TYR195-PRO214

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site_id	PS00210
Number of Residues	9
Details	HEMOCYANIN_2 Arthropod hemocyanins / insect LSPs signature 2. TamRDPvFY

Chain	Residue	Details
A	THR391-TYR399

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site_id	PS00498
Number of Residues	12
Details	TYROSINASE_2 Tyrosinase and hemocyanins CuB-binding region signature. DPvFYrwHsfiD

Chain	Residue	Details
A	ASP395-ASP406

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