8JC5
Crystal structure of PLEKHM1 RUN domain in complex with GTP-bound Arl8b(Q75L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ADP-ribosylation factor-like protein 8B | polymer | 169 | 19400.4 | 2 | UniProt (Q9NVJ2) Pfam (PF00025) | Homo sapiens (human) | ADP-ribosylation factor-like protein 10C,Novel small G protein indispensable for equal chromosome segregation 1 |
| 2 | C, D (C, D) | Pleckstrin homology domain-containing family M member 1 | polymer | 196 | 21899.4 | 2 | UniProt (Q9Y4G2) Pfam (PF02759) | Homo sapiens (human) | PH domain-containing family M member 1,162 kDa adapter protein,AP162 |
| 3 | E, G (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 4 | F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 186 (UniProt: Q9NVJ2)
| PDB | External Database | Details |
|---|---|---|
| Leu 75 | Gln 75 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 82599.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1095.0 | |
| All* | Total formula weight | 83694.6 |
