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8IZN

Structural study of Interferon-induced, double-stranded RNA-activated protein kinase (PKR) and Non-structural protein 1 (NS1) complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AInterferon-induced, double-stranded RNA-activated protein kinasepolymer17919705.41UniProt (P19525)
Pfam (PF00035)
In PDB
Homo sapiens (human)Eukaryotic translation initiation factor 2-alpha kinase 2,eIF-2A protein kinase 2,Interferon-inducible RNA-dependent protein kinase,P1/eIF-2A protein kinase,Protein kinase RNA-activated,PKR,Protein kinase R,Tyrosine-protein kinase EIF2AK2,p68 kinase
2BNon-structural protein 1polymer12213796.01UniProt (Q463W9)
Pfam (PF00600)
In PDB
Influenza A virus (strain A/Memphis/102/1972 H3N2)NS1,NS1A
Sequence modifications
A: 6 - 175 (UniProt: P19525)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ser 2-expression tag
His 3-expression tag
Met 4-expression tag
Glu 5-expression tag
Gly 176-expression tag
Ser 177-expression tag
Gly 178-expression tag
Cys 179-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight33501.4
All*Total formula weight33501.4
*Water molecules are not included.

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PDB entries from 2024-10-09

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