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8IZN

Structural study of Interferon-induced, double-stranded RNA-activated protein kinase (PKR) and Non-structural protein 1 (NS1) complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0003725molecular_functiondouble-stranded RNA binding
B0003723molecular_functionRNA binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000269|Ref.13, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378
ChainResidueDetails
AALA7

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:11152499, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231
ChainResidueDetails
ASER88

site_idSWS_FT_FI3
Number of Residues3
DetailsMOD_RES: Phosphothreonine; by autocatalysis => ECO:0000305|PubMed:11152499
ChainResidueDetails
ATHR93
ATHR94
ATHR95

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:16373505
ChainResidueDetails
ATYR106
ATYR167

site_idSWS_FT_FI5
Number of Residues3
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15) => ECO:0000269|PubMed:23229543
ChainResidueDetails
ALYS74
ALYS164

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PDB entries from 2024-11-06

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