8IZC
Human CK1 Delta Kinase structure bound to Inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Casein kinase I isoform delta | polymer | 291 | 33807.1 | 2 | UniProt (P48730) Pfam (PF00069) | Homo sapiens (human) | CKI-delta,CKId,Tau-protein kinase CSNK1D |
2 | C, D, E, G, H (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
3 | F, I (A, B) | ~{N}5-~{tert}-butyl-2-(3-chloranyl-4-fluoranyl-phenyl)-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-3,5-dicarboxamide | non-polymer | 393.8 | 2 | Chemie (S93) | |||
4 | J, K (A, B) | water | water | 18.0 | 463 | Chemie (HOH) |
Sequence modifications
A, B: 5 - 294 (UniProt: P48730)
PDB | External Database | Details |
---|---|---|
Met 4 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 67614.1 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1268.0 | |
All* | Total formula weight | 68882.1 |