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8IZC

Human CK1 Delta Kinase structure bound to Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Casein kinase I isoform deltapolymer29133807.12UniProt (P48730)
Pfam (PF00069)
Homo sapiens (human)CKI-delta,CKId,Tau-protein kinase CSNK1D
2C, D, E, G, H
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
3F, I
(A, B)
~{N}5-~{tert}-butyl-2-(3-chloranyl-4-fluoranyl-phenyl)-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-3,5-dicarboxamidenon-polymer393.82Chemie (S93)
4J, K
(A, B)
waterwater18.0463Chemie (HOH)
Sequence modifications
A, B: 5 - 294 (UniProt: P48730)
PDBExternal DatabaseDetails
Met 4-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight67614.1
Non-Polymers*Number of molecules7
Total formula weight1268.0
All*Total formula weight68882.1
*Water molecules are not included.

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PDB entries from 2024-11-13

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