8IYJ
Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, H (0, 7) | Cilia- and flagella-associated protein 95 | polymer | 228 | 26633.0 | 2 | UniProt (Q9CQC3) Pfam (PF15139) | Mus musculus (house mouse) | |
| 2 | B, C (1, 2) | EF-hand domain-containing family member B | polymer | 853 | 95892.0 | 2 | UniProt (Q8CDU5) Pfam (PF13499) | Mus musculus (house mouse) | Cilia- and flagella-associated protein 21 |
| 3 | D, E (3, 4) | Cilia- and flagella-associated protein 53 | polymer | 514 | 62036.6 | 2 | UniProt (Q9D439) Pfam (PF13868) | Mus musculus (house mouse) | Coiled-coil domain-containing protein 11 |
| 4 | F, G, TU (5, 6, j1) | Nucleoside diphosphate kinase 7 | polymer | 395 | 44489.8 | 3 | UniProt (Q9QXL8) Pfam (PF00334) | Mus musculus (house mouse) | NDK 7,NDP kinase 7,nm23-M7 |
| 5 | I (8) | Cilia- and flagella-associated protein 107 | polymer | 196 | 23062.5 | 1 | UniProt (Q4KKZ1) Pfam (PF22595) | Mus musculus (house mouse) | |
| 6 | GJ, J (A, N1) | Cilia- and flagella-associated protein 141 | polymer | 101 | 12278.1 | 2 | UniProt (Q9D9D9) Pfam (PF15104) | Mus musculus (house mouse) | |
| 7 | K, L, M, N, O... (A0, A1, A2, A3, A4...) | Tektin-1 | polymer | 418 | 48713.0 | 6 | UniProt (Q9DAJ2) Pfam (PF03148) | Mus musculus (house mouse) | |
| 8 | AA, AB, AD, AE, AF... (AA, AC, AE, AG, AI...) | Tubulin alpha-3 chain | polymer | 450 | 50012.4 | 178 | UniProt (P05214) Pfam (PF03953) Pfam (PF00091) | Mus musculus (house mouse) | Alpha-tubulin 3/7,Alpha-tubulin isotype M-alpha-3/7,Tubulin alpha-3/alpha-7 chain |
| 9 | AJ, AN, AP, BA, BB... (AB, AD, AF, AH, AJ...) | Tubulin beta-4B chain | polymer | 445 | 49877.8 | 176 | UniProt (P68372) Pfam (PF00091) Pfam (PF03953) | Mus musculus (house mouse) | Tubulin beta-2C chain |
| 10 | CB, GA (B, C) | Meiosis-specific nuclear structural protein 1 | polymer | 491 | 60353.0 | 2 | UniProt (Q61884) Pfam (PF13868) | Mus musculus (house mouse) | |
| 11 | HA, IA, JA, KA, LA... (B0, B1, B2, B3, B4...) | Tektin-2 | polymer | 430 | 50385.1 | 12 | UniProt (Q922G7) Pfam (PF03148) | Mus musculus (house mouse) | Tektin-t,Testicular tektin |
| 12 | DB, EB, FB, GB, HB... (C0, C1, C2, C3, C4...) | Tektin-3 | polymer | 490 | 56754.8 | 17 | UniProt (Q6X6Z7) Pfam (PF03148) | Mus musculus (house mouse) | |
| 13 | AC, BH (D, K3) | Sperm-associated antigen 8 | polymer | 470 | 50591.8 | 2 | UniProt (Q3V0Q6) Pfam (PF22584) | Mus musculus (house mouse) | Sperm membrane protein 1,SMP-1,Sperm membrane protein BS-84 |
| 14 | BC, CC, DC, EC, FC... (D0, D1, D2, D3, D4...) | Tektin-4 | polymer | 447 | 52121.4 | 12 | UniProt (Q149S1) Pfam (PF03148) | Mus musculus (house mouse) | Testicular microtubules-related protein 4 |
| 15 | HJ, ND, XC (E, F, N2) | Cilia- and flagella-associated protein 161 | polymer | 303 | 34433.4 | 3 | UniProt (Q6P8Y0) | Mus musculus (house mouse) | |
| 16 | DE (G) | Piercer of microtubule wall 2 protein | polymer | 122 | 13728.5 | 1 | UniProt (V9GXK1) Pfam (PF14892) | Mus musculus (house mouse) | |
| 17 | CG, FJ, FK, GK, GL... (H, I, J, K, L...) | Protein FAM166A | polymer | 319 | 36659.6 | 16 | UniProt (Q9D4K5) Pfam (PF10629) | Mus musculus (house mouse) | |
| 18 | LF (I1) | Cilia- and flagella-associated protein 68 | polymer | 166 | 19552.7 | 1 | UniProt (Q9D131) Pfam (PF06608) | Mus musculus (house mouse) | |
| 19 | DG, EG, FG, GG, HG (J1, J2, J3, J4, J5) | Cilia and flagella-associated protein 77 | polymer | 283 | 32786.0 | 5 | UniProt (A0A087WRI3) Pfam (PF14825) | Mus musculus (house mouse) | |
| 20 | AH, ZG (K1, K2) | Family with sequence similarity 183, member B | polymer | 137 | 16357.5 | 2 | UniProt (D2D553) Pfam (PF14886) UniProt (by SIFTS) (Q5NC57) | Mus musculus (house mouse) | Testis highly expressed protein 6 |
| 21 | TH (L1) | Cilia- and flagella-associated protein 90 | polymer | 182 | 20886.4 | 1 | UniProt (Q9DAR0) Pfam (PF15074) | Mus musculus (house mouse) | Y regulated sperm protein |
| 22 | LI, MI, NI, OI (M1, M2, M3, M4) | Protein FAM166C | polymer | 200 | 23098.0 | 4 | UniProt (Q9DAS2) Pfam (PF10629) | Mus musculus (house mouse) | |
| 23 | XL, YJ, YK (O, P, Q) | RIB43A-like with coiled-coils protein 1 | polymer | 379 | 45032.2 | 3 | UniProt (Q9D0B8) Pfam (PF05914) | Mus musculus (house mouse) | |
| 24 | AK, BK, CK, ZJ (O1, O2, O3, O4) | Dual specificity phosphatase 21 | polymer | 189 | 21527.6 | 4 | UniProt (Q9D9D8) Pfam (PF00782) | Mus musculus (house mouse) | |
| 25 | DK, EK, HP, HQ, MO (O5, O6, T, U, V) | EF-hand domain-containing protein 1 | polymer | 648 | 75235.4 | 5 | UniProt (Q9D9T8) Pfam (PF06565) Pfam (PF13499) | Mus musculus (house mouse) | Myoclonin-1 |
| 26 | AL, ZK (P1, P2) | Testis expressed 49 | polymer | 131 | 15528.6 | 2 | UniProt (Q8CDT5) Pfam (PF22593) | Mus musculus (house mouse) | |
| 27 | BL, CL, DL, EL, FL (P3, P4, P5, P6, P7) | Testis-expressed sequence 37 protein | polymer | 180 | 21069.1 | 5 | UniProt (Q9DAG4) Pfam (PF15217) | Mus musculus (house mouse) | |
| 28 | AM, BM, CM, YL, ZL (Q1, Q2, Q3, Q4, Q5) | Tektin bundle-interacting protein 1 | polymer | 206 | 23987.3 | 5 | UniProt (A6H6Q4) Pfam (PF15041) | Mus musculus (house mouse) | |
| 29 | NN, SM (R, S) | RIB43A-like with coiled-coils protein 2 | polymer | 377 | 45328.2 | 2 | UniProt (Q9D4Q1) Pfam (PF05914) | Mus musculus (house mouse) | |
| 30 | IP, IQ, IR, JP, JQ... (U0, U1, U2, U3, U4...) | Tektin-5 | polymer | 557 | 62817.5 | 26 | UniProt (G5E8A8) Pfam (PF03148) | Mus musculus (house mouse) | |
| 31 | ES, HR, LT, WS (W, X, Y, Z) | EF-hand domain-containing family member C2 | polymer | 750 | 87758.0 | 4 | UniProt (Q9D485) Pfam (PF06565) | Mus musculus (house mouse) | |
| 32 | FS, GS, HS, IS (X0, X1, X2, X3) | Spermatid-specific manchette-related protein 1 | polymer | 260 | 29977.2 | 4 | UniProt (Q2MH31) Pfam (PF15181) | Mus musculus (house mouse) | Ciliated bronchial epithelial protein 1 |
| 33 | JS, KS (X4, X5) | Protein phosphatase 1 regulatory subunit 32 | polymer | 427 | 47873.1 | 2 | UniProt (Q148A4) Pfam (PF15691) | Mus musculus (house mouse) | Protein IIIG9 |
| 34 | LS, MS, NS (X6, X7, X8) | Testis-specific serine/threonine-protein kinase 6 | polymer | 273 | 30332.9 | 3 | UniProt (Q925K9) Pfam (PF00069) | Mus musculus (house mouse) | TSK-6,TSSK-6,Testis-specific kinase 6,Serine/threonine-protein kinase SSTK,Small serine/threonine kinase |
| 35 | OS, PS, QS, RS, SS... (XA, XB, XC, XD, XE...) | Cilia- and flagella-associated protein 20 | polymer | 193 | 22781.4 | 8 | UniProt (Q8BTU1) Pfam (PF05018) | Mus musculus (house mouse) | Gene trap locus 3 protein |
| 36 | AT, BT, CT, XS, YS... (Y0, Y1, Y2, Y3, Y4...) | Outer dense fiber protein 3 | polymer | 254 | 27691.0 | 6 | UniProt (Q920N1) Pfam (PF07004) | Mus musculus (house mouse) | Outer dense fiber of sperm tails protein 3,Sperm tail protein SHIPPO 1 |
| 37 | DT, ET, FT, GT, HT... (YA, YB, YC, YD, YE...) | Parkin coregulated gene protein homolog | polymer | 241 | 27763.3 | 8 | UniProt (Q9DAK2) Pfam (PF10274) | Mus musculus (house mouse) | Hypertension-related protein 1-like protein,PARK2 coregulated gene protein |
| 38 | MT (Z1) | Testis, prostate and placenta-expressed protein | polymer | 216 | 24985.7 | 1 | UniProt (Q6IMH0) Pfam (PF22574) | Mus musculus (house mouse) | |
| 39 | DU, EU, RT, WT, XT (a, a6, b, c, d) | Cilia- and flagella-associated protein 45 | polymer | 551 | 65962.0 | 5 | UniProt (Q9D9U9) Pfam (PF13868) | Mus musculus (house mouse) | Coiled-coil domain-containing protein 19,Nasopharyngeal epithelium-specific protein 1 |
| 40 | ST, TT, UT, VT (a1, a2, a3, a4) | Uncharacterized protein C10orf82 homolog | polymer | 229 | 25847.5 | 4 | UniProt (Q9CQT6) Pfam (PF22573) | Mus musculus (house mouse) | |
| 41 | AU, BU, CU, YT, ZT (b1, b2, b3, b4, b5) | Coiled-coil domain-containing protein 105 | polymer | 499 | 57406.5 | 5 | UniProt (Q9D4K7) Pfam (PF03148) | Mus musculus (house mouse) | |
| 42 | FU, GU, HU (e, f, g) | Cilia- and flagella-associated protein 52 | polymer | 620 | 68322.2 | 3 | UniProt (Q5F201) Pfam (PF00400) | Mus musculus (house mouse) | WD repeat-containing protein 16 |
| 43 | IU, NU, SU, UU (h, i, j, k) | Enkurin | polymer | 255 | 29587.5 | 4 | UniProt (Q6SP97) Pfam (PF13864) | Mus musculus (house mouse) | |
| 44 | JU, KU, LU, MU (h1, h2, h3, h4) | Testis-expressed protein 43 | polymer | 141 | 16305.6 | 4 | UniProt (Q9D9I1) Pfam (PF14983) | Mus musculus (house mouse) | |
| 45 | OU, VU, WU, XU (i1, l, m, n) | Protein Flattop | polymer | 189 | 20575.1 | 4 | UniProt (Q6P8X9) Pfam (PF22611) | Mus musculus (house mouse) | Cilia- and flagella-associated protein 126 |
| 46 | PU, QU, RU (i2, i3, i4) | EF-hand calcium-binding domain-containing protein 6 | polymer | 1516 | 176028.3 | 3 | UniProt (Q6P1E8) Pfam (PF13202) Pfam (PF13833) Pfam (PF08976) Pfam (PF13499) | Mus musculus (house mouse) | DJ-1-binding protein,DJBP |
| 47 | YU, ZU (o, p) | Cilia- and flagella-associated protein 210 | polymer | 547 | 65266.5 | 2 | UniProt (A0JLY1) Pfam (PF13868) | Mus musculus (house mouse) | Coiled-coil domain-containing protein 173 |
| 48 | AV, BV, CV (q, r, s) | Cilia- and flagella-associated protein 276 | polymer | 168 | 18960.1 | 3 | UniProt (Q9DAD0) Pfam (PF12494) | Mus musculus (house mouse) | |
| 49 | DV (y) | Piercer of microtubule wall 1 protein | polymer | 167 | 18862.9 | 1 | UniProt (Q5BN45) Pfam (PF14892) | Mus musculus (house mouse) | Pierce1,p53-induced expression in RB-null cells protein 1 |
| 50 | AAA, ABA, ACA, AEA, AFA... (FG, GI, HK, JO, KO...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 178 | Chemie (GTP) | |||
| 51 | AHA, AJA, ALA, AW, AX... (NA, PE, RK, AO, CC...) | MAGNESIUM ION | non-polymer | 24.3 | 178 | Chemie (MG) | |||
| 52 | ADA, AGA, AKA, ANA, AOA... (IL, LP, QH, UB, VD...) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 176 | Chemie (GDP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 576 |
| Total formula weight | 27729286.4 | |
| Non-Polymers* | Number of molecules | 532 |
| Total formula weight | 175455.7 | |
| All* | Total formula weight | 27904742.1 |
