8IVU
Crystal Structure of Human NAMPT in complex with A4276
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Nicotinamide phosphoribosyltransferase | polymer | 491 | 55594.9 | 4 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) In PDB | Homo sapiens (human) | NAmPRTase,Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
| 2 | A, B, C, D | N-[[4-(6-methyl-1,3-benzoxazol-2-yl)phenyl]methyl]pyridine-3-carboxamide | non-polymer | 343.4 | 4 | Chemie (SJ6) | |||
| 3 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 12 | Chemie (PO4) | |||
| 4 | water | water | 18.0 | 710 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 222379.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2513.2 | |
| All* | Total formula weight | 224892.9 |
