8IM2

Crystal structure of human HPPD complexed with NTBC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	4-hydroxyphenylpyruvate dioxygenase	polymer	393	44996.3	6	UniProt (P32754) Pfam (PF00903)	Homo sapiens (human)	4-hydroxyphenylpyruvic acid oxidase,4HPPD,HPD,HPPDase
2	G, J, M, Q, S... (A, B, C, D, E...)	COBALT (II) ION	non-polymer		58.9	6	Chemie (CO)
3	H, K, N, R, T... (A, B, C, D, E...)	2-{HYDROXY[2-NITRO-4-(TRIFLUOROMETHYL)PHENYL]METHYLENE}CYCLOHEXANE-1,3-DIONE	non-polymer		329.2	6	Chemie (NTD)
4	I, L, O, P, U... (A, B, C, D, E...)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	6	Chemie (MPD)
5	AA, BA, CA, Y, Z (C, D, E, A, B)	water	water		18.0	83	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	269977.5
Non-Polymers*	Number of molecules	18
	Total formula weight	3038.0
All*	Total formula weight	273015.5

*Water molecules are not included.