8IF3
Structure of human alpha-2/delta-1 with mirogabalin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Voltage-dependent calcium channel subunit alpha-2/delta-1 | polymer | 1099 | 124413.1 | 1 | UniProt (P54289) Pfam (PF08399) Pfam (PF00092) Pfam (PF08473) | Homo sapiens (human) | Voltage-gated calcium channel subunit alpha-2/delta-1 |
| 2 | B, C (C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, E, F, G, I... (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 4 | H (A) | 2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid | non-polymer | 209.3 | 1 | Chemie (8X9) |
Sequence modifications
A: 1 - 1091 (UniProt: P54289)
| PDB | External Database | Details |
|---|---|---|
| His 677 | - | insertion |
| His 677 | - | insertion |
| His 677 | - | insertion |
| His 677 | - | insertion |
| His 677 | - | insertion |
| His 677 | - | insertion |
| His 677 | - | insertion |
| His 677 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 124413.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1757.7 | |
| All* | Total formula weight | 127019.6 |
