8I5W

Crystal structure of the DHR-2 domain of DOCK10 in complex with Rac1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Dedicator of cytokinesis protein 10	polymer	282	32603.9	1	UniProt (Q8BZN6) Pfam (PF20422) Pfam (PF20421) In PDB	Mus musculus (house mouse)	Zizimin-3
2	B	Ras-related C3 botulinum toxin substrate 1	polymer	184	20230.2	1	UniProt (P63000) Pfam (PF00071) In PDB	Homo sapiens (human)	Cell migration-inducing gene 5 protein,Ras-like protein TC25,p21-Rac1
3	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	144	Chemie (HOH)

Sequence modifications

A: 1875 - 2150 (UniProt: Q8BZN6)

PDB	External Database	Details
Gly 1869	-	expression tag
Ser 1870	-	expression tag
Ser 1871	-	expression tag
Gly 1872	-	expression tag
Ser 1873	-	expression tag
Ser 1874	-	expression tag

B: 1 - 177 (UniProt: P63000)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52834.2
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	52930.2

*Water molecules are not included.