8I5W
Crystal structure of the DHR-2 domain of DOCK10 in complex with Rac1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dedicator of cytokinesis protein 10 | polymer | 282 | 32603.9 | 1 | UniProt (Q8BZN6) Pfam (PF20422) Pfam (PF20421) | Mus musculus (house mouse) | Zizimin-3 |
| 2 | B (B) | Ras-related C3 botulinum toxin substrate 1 | polymer | 184 | 20230.2 | 1 | UniProt (P63000) Pfam (PF00071) | Homo sapiens (human) | Cell migration-inducing gene 5 protein,Ras-like protein TC25,p21-Rac1 |
| 3 | C (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 1875 - 2150 (UniProt: Q8BZN6)
B: 1 - 177 (UniProt: P63000)
| PDB | External Database | Details |
|---|---|---|
| Gly 1869 | - | expression tag |
| Ser 1870 | - | expression tag |
| Ser 1871 | - | expression tag |
| Gly 1872 | - | expression tag |
| Ser 1873 | - | expression tag |
| Ser 1874 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52834.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 52930.2 |
