8I0B
The crystal structure of human glutamate receptor 2 in complex with LT-102
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glutamate receptor 2,Isoform Flip of Glutamate receptor 2 | polymer | 301 | 33115.3 | 2 | UniProt (P23819) UniProt (P42262) Pfam (PF10613) Pfam (PF00060) | Mus musculus (house mouse) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | C, D, E, F (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | G (B) | 8-[4-(2-fluorophenyl)phenyl]-3,4-dihydro-1,2$l^{6},3-benzoxathiazine 2,2-dioxide | non-polymer | 355.4 | 1 | Chemie (NXO) | |||
| 4 | H (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | I (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 117 (UniProt: P23819)
A, B: 120 - 301 (UniProt: P42262)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Gly 118 | - | linker |
| Thr 119 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66230.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 798.1 | |
| All* | Total formula weight | 67028.7 |
