8I0B

The crystal structure of human glutamate receptor 2 in complex with LT-102

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20614889","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XHD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20614889","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21531559","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3R7X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20614889","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21531559","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XHD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"source":"UniProtKB","id":"P19491","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PKG","evidences":[{"source":"UniProtKB","id":"P19491","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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