8I0B
The crystal structure of human glutamate receptor 2 in complex with LT-102
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P42262 |
| Chain | Residue | Details |
| A | PRO89 | |
| A | THR91 | |
| A | ARG96 | |
| B | PRO89 | |
| B | THR91 | |
| B | ARG96 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20614889, ECO:0007744|PDB:2XHD |
| Chain | Residue | Details |
| A | SER142 | |
| A | THR143 | |
| B | SER142 | |
| B | THR143 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20614889, ECO:0000269|PubMed:21531559, ECO:0007744|PDB:2XHD |
| Chain | Residue | Details |
| A | GLU193 | |
| B | GLU193 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKC => ECO:0000250|UniProtKB:P19491 |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PKG => ECO:0000250|UniProtKB:P19491 |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=M4 |
| Chain | Residue | Details |
| A | VAL280-ILE300 | |
| B | VAL280-ILE300 |
