8HO4
Falcilysin in complex with MMV000848
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Falcilysin | polymer | 1158 | 135039.4 | 1 | UniProt (Q76NL8) Pfam (PF00675) Pfam (PF05193) Pfam (PF08367) Pfam (PF22516) | Plasmodium falciparum 3D7 | |
| 2 | B (A) | (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol | non-polymer | 308.4 | 1 | Chemie (XUH) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | G (A) | water | water | 18.0 | 703 | Chemie (HOH) |
Sequence modifications
A: 59 - 1193 (UniProt: Q76NL8)
| PDB | External Database | Details |
|---|---|---|
| Met 36 | - | initiating methionine |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| His 40 | - | expression tag |
| His 41 | - | expression tag |
| His 42 | - | expression tag |
| Ser 43 | - | expression tag |
| Ser 44 | - | expression tag |
| Gly 45 | - | expression tag |
| Val 46 | - | expression tag |
| Asp 47 | - | expression tag |
| Leu 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Thr 50 | - | expression tag |
| Glu 51 | - | expression tag |
| Asn 52 | - | expression tag |
| Leu 53 | - | expression tag |
| Tyr 54 | - | expression tag |
| Phe 55 | - | expression tag |
| Gln 56 | - | expression tag |
| Ser 57 | - | expression tag |
| Met 58 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 135039.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 560.0 | |
| All* | Total formula weight | 135599.4 |
