8HO4

Falcilysin in complex with MMV000848

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0005773	cellular_component	vacuole
A	0005774	cellular_component	vacuolar membrane
A	0006508	biological_process	proteolysis
A	0008237	molecular_function	metallopeptidase activity
A	0016020	cellular_component	membrane
A	0016485	biological_process	protein processing
A	0020011	cellular_component	apicoplast
A	0020020	cellular_component	food vacuole
A	0031982	cellular_component	vesicle
A	0042540	biological_process	hemoglobin catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10096

Chain	Residue	Details
A	GLU132

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|Ref.6, ECO:0007744|PDB:3S5K, ECO:0007744|PDB:3S5M

Chain	Residue	Details
A	HIS129
A	HIS133
A	GLU243

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