8HCF
Crystal structure of mTREX1-UMP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Three-prime repair exonuclease 1 | polymer | 250 | 27395.1 | 2 | UniProt (Q91XB0) | Mus musculus (house mouse) | 3'-5' exonuclease TREX1 |
| 2 | C (A) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 3 | D, E, G (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (B) | URIDINE-5'-MONOPHOSPHATE | non-polymer | 324.2 | 1 | Chemie (U5P) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 564 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 242 (UniProt: Q91XB0)
| PDB | External Database | Details |
|---|---|---|
| Leu 243 | - | expression tag |
| Glu 244 | - | expression tag |
| His 245 | - | expression tag |
| His 246 | - | expression tag |
| His 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54790.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 850.7 | |
| All* | Total formula weight | 55640.9 |
