8HB5
Crystal structure of Mincle in complex with HD-275
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | C-type lectin domain family 4 member E | polymer | 151 | 17443.5 | 1 | UniProt (E1BHM0) Pfam (PF00059) | Bos taurus (cattle) | |
| 2 | B, C, D (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) PubChem (271) | |||
| 3 | E (A) | (2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrol | non-polymer | 194.2 | 1 | Chemie (L6N) PubChem (21722580) PubChem (21722581) PubChem (26176683) PubChem (44269524) PubChem (51548332) PubChem (55250368) PubChem (321651) PubChem (59451317) PubChem (89040318) PubChem (89042466) PubChem (90672358) PubChem (91617326) PubChem (91820740) PubChem (91820744) PubChem (102476143) PubChem (117767347) PubChem (10313507) PubChem (13832658) PubChem (13832659) PubChem (168363563) PubChem (130935042) PubChem (132033921) PubChem (145097923) PubChem (168083859) PubChem (168356387) PubChem (168356392) PubChem (168359685) PubChem (168359974) PubChem (168362365) PubChem (168363584) PubChem (168366076) PubChem (168370319) PubChem (173719430) | |||
| 4 | F (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 64 - 211 (UniProt: E1BHM0)
| PDB | External Database | Details |
|---|---|---|
| Gly 61 | - | expression tag |
| Ser 62 | - | expression tag |
| Ala 63 | - | expression tag |
| Thr 174 | Ile 174 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17443.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 314.4 | |
| All* | Total formula weight | 17757.9 |






