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8HB5

Crystal structure of Mincle in complex with HD-275

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
C-type lectin domain family 4 member Epolymer15117443.51UniProt (E1BHM0)
Pfam (PF00059)
Bos taurus (cattle)
2B, C, D
(A)
CALCIUM IONnon-polymer40.13Chemie (CA)
3E
(A)
(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(methoxymethyl)oxane-2,3,4,5-tetrolnon-polymer194.21Chemie (L6N)
4F
(A)
waterwater18.03Chemie (HOH)
Sequence modifications
A: 64 - 211 (UniProt: E1BHM0)
PDBExternal DatabaseDetails
Gly 61-expression tag
Ser 62-expression tag
Ala 63-expression tag
Thr 174Ile 174engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17443.5
Non-Polymers*Number of molecules4
Total formula weight314.4
All*Total formula weight17757.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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