8H75
FGFR2 in complex with YJ001
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Fibroblast growth factor receptor 2 | polymer | 312 | 35799.1 | 4 | UniProt (P21802) Pfam (PF07714) | Homo sapiens (human) | FGFR-2,K-sam,KGFR,Keratinocyte growth factor receptor |
| 2 | E, G, H, I (A, B, C, D) | Tinengotinib | non-polymer | 394.9 | 4 | Chemie (KX0) | |||
| 3 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 459 - 768 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Gly 457 | - | expression tag |
| His 458 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 143196.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1614.9 | |
| All* | Total formula weight | 144811.4 |
