8GZ5
Crystal structure of neutralizing VHH P17 in complex with SARS-CoV-2 Alpha variant spike receptor-binding domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Spike protein S1 | polymer | 206 | 23373.2 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
2 | B | Nanobody P17 | polymer | 126 | 13574.0 | 1 | Vicugna pacos | ||
3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
5 | water | water | 18.0 | 382 | Chemie (HOH) |
Sequence modifications
A: 333 - 530 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Tyr 501 | Asn 501 | variant |
His 531 | - | expression tag |
His 532 | - | expression tag |
His 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36947.2 | |
Branched | Number of molecules | 1 |
Total formula weight | 570.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 744.8 | |
All* | Total formula weight | 38262.6 |