8GTJ
Crystal structure of IpaH7.8-LRR and GSDMB isoform-4 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Isoform 4 of Gasdermin-B | polymer | 414 | 47128.6 | 2 | UniProt (Q8TAX9) Pfam (PF04598) Pfam (PF17708) In PDB | Homo sapiens (human) | Gasdermin-like protein |
2 | B, D | Probable E3 ubiquitin-protein ligase ipaH7.8 | polymer | 241 | 27840.5 | 2 | UniProt (P18014) Pfam (PF12468) In PDB | Shigella flexneri | Probable RING-type E3 ubiquitin transferase ipaH7.8 |
3 | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 407 (UniProt: Q8TAX9)
B, D: 23 - 262 (UniProt: P18014)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Pro -5 | - | expression tag |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Gly -2 | - | expression tag |
Arg -1 | - | expression tag |
Pro 0 | - | expression tag |
- | Glu 234 | deletion |
- | Lys 235 | deletion |
- | Asp 236 | deletion |
- | Gly 237 | deletion |
- | Ala 238 | deletion |
- | Ser 239 | deletion |
- | Ser 240 | deletion |
- | Cys 241 | deletion |
- | Leu 242 | deletion |
PDB | External Database | Details |
---|---|---|
Met 22 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 149938.1 | |
All* | Total formula weight | 149938.1 |