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8GHP

GUCY2C-ECD bound to anti-GUCY2C-scFv antibody

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanylyl cyclase Cpolymer42147410.51UniProt (P25092)Homo sapiens (human)GC-C,Heat-stable enterotoxin receptor,STA receptor,hSTAR,Intestinal guanylate cyclase
2B
(H)
anti-GUCY2C-scFv antibody heavy chainpolymer12213637.31Homo sapiens (human)
3C
(L)
anti-GUCY2C-scFv antibody light chainpolymer11912983.41Homo sapiens (human)
4D
(S)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched627.61In PDB
GlyTouCan (G47362BJ)
Sequence modifications
A: 1 - 407 (UniProt: P25092)
PDBExternal DatabaseDetails
Ser -2-expression tag
Thr -1-expression tag
Gly 0-expression tag
Gly 408-expression tag
Gly 409-expression tag
Gly 410-expression tag
Gly 411-expression tag
Ser 412-expression tag
Glu 413-expression tag
Asn 414-expression tag
Leu 415-expression tag
Tyr 416-expression tag
Phe 417-expression tag
Gln 418-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight74031.1
BranchedNumber of molecules1
Total formula weight627.6
All*Total formula weight74658.7
*Water molecules are not included.

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PDB entries from 2026-01-21

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