8GHP
GUCY2C-ECD bound to anti-GUCY2C-scFv antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanylyl cyclase C | polymer | 421 | 47410.5 | 1 | UniProt (P25092) | Homo sapiens (human) | GC-C,Heat-stable enterotoxin receptor,STA receptor,hSTAR,Intestinal guanylate cyclase |
| 2 | B (H) | anti-GUCY2C-scFv antibody heavy chain | polymer | 122 | 13637.3 | 1 | Homo sapiens (human) | ||
| 3 | C (L) | anti-GUCY2C-scFv antibody light chain | polymer | 119 | 12983.4 | 1 | Homo sapiens (human) | ||
| 4 | D (S) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB GlyTouCan (G47362BJ) |
Sequence modifications
A: 1 - 407 (UniProt: P25092)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Thr -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 408 | - | expression tag |
| Gly 409 | - | expression tag |
| Gly 410 | - | expression tag |
| Gly 411 | - | expression tag |
| Ser 412 | - | expression tag |
| Glu 413 | - | expression tag |
| Asn 414 | - | expression tag |
| Leu 415 | - | expression tag |
| Tyr 416 | - | expression tag |
| Phe 417 | - | expression tag |
| Gln 418 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74031.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 627.6 | |
| All* | Total formula weight | 74658.7 |






