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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8GF8

Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DTransient receptor potential cation channel subfamily V member 1polymer1102124575.34UniProt (Q8NER1)
Pfam (PF12796)
Pfam (PF00023)
Pfam (PF00520)
In PDB		Homo sapiens (human)TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1
2B, C, A, D(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.136Chemie (POV)
3C, A, D, B(2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoatenon-polymer867.14Chemie (8IJ)
4ASODIUM IONnon-polymer23.02Chemie (NA)
Sequence modifications
A, B, C, D: 2 - 839 (UniProt: Q8NER1)
PDBExternal DatabaseDetails
Met -1-initiating methionine
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Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight498301.1
Non-Polymers*Number of molecules42
Total formula weight30877.3
All*Total formula weight529178.4
*Water molecules are not included.

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PDB entries from 2024-07-24

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