8FVF
Bromodomain of EP300 liganded with CCS-1477
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone acetyltransferase p300 | polymer | 114 | 13608.5 | 2 | UniProt (Q09472) Pfam (PF00439) | Homo sapiens (human) | p300 HAT,E1A-associated protein p300,Histone butyryltransferase p300,Histone crotonyltransferase p300,Protein 2-hydroxyisobutyryltransferase p300,Protein lactyltransferas p300,Protein propionyltransferase p300 |
| 2 | C, K (A, B) | (6S)-1-[3,4-bis(fluoranyl)phenyl]-6-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(4-methoxycyclohexyl)benzimidazol-2-yl]piperidin-2-one | non-polymer | 534.6 | 2 | Chemie (JHL) | |||
| 3 | D, L, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | E, F, G, H, I... (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 9 | Chemie (NI) | |||
| 5 | N (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 219 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27217.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1879.7 | |
| All* | Total formula weight | 29096.7 |
