8FTA
Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein polybromo-1 | polymer | 116 | 13231.3 | 1 | UniProt (Q86U86) Pfam (PF00439) | Homo sapiens (human) | hPB1,BRG1-associated factor 180,BAF180,Polybromo-1D |
| 2 | B (A) | (2S)-5-chloro-2-(3-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one | non-polymer | 272.7 | 1 | Chemie (Y8X) | |||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A: 178 - 291 (UniProt: Q86U86)
| PDB | External Database | Details |
|---|---|---|
| Ser 176 | - | expression tag |
| Met 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13231.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 403.5 | |
| All* | Total formula weight | 13634.8 |
