8FJ3

Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7(Y13A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Evasin P1243	polymer	101	11114.5	1	UniProt (A0A0C9S461) Pfam (PF19429)	Amblyomma americanum (Lone Star tick)
2	B (B)	C-C motif chemokine 7	polymer	76	8882.4	1	UniProt (P80098) Pfam (PF00048)	Homo sapiens (human)	Monocyte chemoattractant protein 3,Monocyte chemotactic protein 3,MCP-3,NC28,Small-inducible cytokine A7
3	C, D (A, B)	water	water		18.0	78	Chemie (HOH)

Sequence modifications

A: 4 - 103 (UniProt: A0A0C9S461)

PDB	External Database	Details
Gly 3	-	expression tag

B: 1 - 76 (UniProt: P80098)

PDB	External Database	Details
Ala 13	Tyr 36	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	19996.8
All*	Total formula weight	19996.8

*Water molecules are not included.