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8FJ3

Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7(Y13A)

Functional Information from GO Data
ChainGOidnamespacecontents
A0019957molecular_functionC-C chemokine binding
A1900137biological_processnegative regulation of chemokine activity
B0002548biological_processmonocyte chemotaxis
B0005125molecular_functioncytokine activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006874biological_processintracellular calcium ion homeostasis
B0006935biological_processchemotaxis
B0006954biological_processinflammatory response
B0006955biological_processimmune response
B0007010biological_processcytoskeleton organization
B0007165biological_processsignal transduction
B0007267biological_processcell-cell signaling
B0008009molecular_functionchemokine activity
B0008201molecular_functionheparin binding
B0008360biological_processregulation of cell shape
B0010332biological_processresponse to gamma radiation
B0030335biological_processpositive regulation of cell migration
B0031726molecular_functionCCR1 chemokine receptor binding
B0031727molecular_functionCCR2 chemokine receptor binding
B0048020molecular_functionCCR chemokine receptor binding
B0048245biological_processeosinophil chemotaxis
B0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
B0070098biological_processchemokine-mediated signaling pathway
B0071361biological_processcellular response to ethanol
B2000503biological_processpositive regulation of natural killer cell chemotaxis
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:15340161
ChainResidueDetails
BGLN1
AASN12
AASN32
AASN35
AASN49
AASN63
AASN77
AASN93

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN6

226707

PDB entries from 2024-10-30

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