8F93
WDR5 covalently modified at Y228 by (R)-2-SF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | WD repeat-containing protein 5 | polymer | 316 | 34663.3 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | BMP2-induced 3-kb gene protein |
| 2 | C, G (A, B) | 3-ethynyl-5-{[(3R)-4-{1-[(2-methoxyphenyl)methyl]-1H-benzimidazole-5-carbonyl}-3-methylpiperazin-1-yl]methyl}benzene-1-sulfonyl fluoride | non-polymer | 560.6 | 2 | Chemie (XKN) | |||
| 3 | D, H, I, J (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | E, K (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | - | expression tag |
| Asn 20 | - | expression tag |
| Ala 21 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69326.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1752.7 | |
| All* | Total formula weight | 71079.2 |
