8F8W
Crystal structure of Nb.X0 bound to the afucosylated human IgG1 fragment crystal form I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (A, B, E, F) | afucosylated IgG1 fragment | polymer | 224 | 25357.8 | 4 | UniProt (Q6MZV7) Pfam (PF07654) | Homo sapiens (human) | Uncharacterized protein DKFZp686C11235 |
| 2 | C, D, G, H (C, D, G, H) | Nb.X0 | polymer | 120 | 13105.5 | 4 | Camelidae mixed library | ||
| 3 | I, J, K, L (I, J, K, L) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1317.2 | 4 | In PDB GlyTouCan (G39213VZ) | |||
| 4 | M, N, O, P, Q (A, B, C, E, F) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A, B, E, F: 221 - 444 (UniProt: Q6MZV7)
| PDB | External Database | Details |
|---|---|---|
| Arg 382 | Glu 408 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 153853.2 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 5268.8 | |
| All* | Total formula weight | 159122.0 |
