8F8M
LRH-1 bound to small molecule Tet and fragment of coactivator Tif2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Nuclear receptor subfamily 5 group A member 2 | polymer | 246 | 28401.8 | 1 | UniProt (O00482) Pfam (PF00104) | Homo sapiens (human) | Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1 |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 14 | 1708.9 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | C (A) | (1~{R},3~{a}~{R},6~{a}~{R})-4-phenyl-3~{a}-(1-phenylethenyl)-5-[9-(1~{H}-1,2,3,4-tetrazol-5-yl)nonyl]-2,3,6,6~{a}-tetrahydro-1~{H}-pentalen-1-ol | non-polymer | 496.7 | 1 | Chemie (XKE) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 299 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Ser 296 | - | expression tag |
| Asn 297 | - | expression tag |
| Ala 298 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30110.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 496.7 | |
| All* | Total formula weight | 30607.4 |
