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8F09

Crystal structure of a trimethoprim-resistant dihydrofolate reductase (DHFR) enzyme from an uncultured soil bacterium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BDihydrofolate reductasepolymer16719225.92UniProt (A0A8A1VA22)
Pfam (PF00186)
In PDB
uncultured bacteriumDHFR
2A, BSULFATE IONnon-polymer96.15Chemie (SO4)
3waterwater18.072Chemie (HOH)
Sequence modifications
A, B: 1 - 166 (UniProt: A0A8A1VA22)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight38451.8
Non-Polymers*Number of molecules5
Total formula weight480.3
All*Total formula weight38932.1
*Water molecules are not included.

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