8EZA

NHEJ Long-range complex with PAXX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	S, T	Protein PAXX	polymer	204	21663.5	2	UniProt (Q9BUH6) Pfam (PF15384) In PDB	Homo sapiens (human)	Paralog of XRCC4 and XLF,XRCC4-like small protein
2	J, A	X-ray repair cross-complementing protein 6	polymer	609	69945.0	2	UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037) In PDB	Homo sapiens (human)
3	K, B	X-ray repair cross-complementing protein 5	polymer	732	82812.4	2	UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785) In PDB	Homo sapiens (human)
4	L, C	DNA-dependent protein kinase catalytic subunit	polymer	4128	469673.2	2	UniProt (P78527) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260) Pfam (PF20502) In PDB	Homo sapiens (human)
5	R, Q	PRKDC_HUMAN DNA-dependent protein kinase catalytic subunit -- Unknown region	polymer	20	1720.1	2		Homo sapiens
6	M, D	DNA (31-MER)	polymer	31	9510.2	2		Homo sapiens
7	N, E	DNA (30-MER)	polymer	30	9237.0	2		Homo sapiens
8	H, I	Non-homologous end-joining factor 1	polymer	299	33372.2	2	UniProt (Q9H9Q4) Pfam (PF09302) Pfam (PF21928) In PDB	Homo sapiens (human)	Protein cernunnos,XRCC4-like factor
9	F, G, O, P	DNA repair protein XRCC4	polymer	336	38337.7	4	UniProt (Q13426) Pfam (PF06632) Pfam (PF21924) Pfam (PF21925) In PDB	Homo sapiens (human)	X-ray repair cross-complementing protein 4
10	X, Y	DNA ligase 4	polymer	911	104125.0	2	UniProt (P49917) Pfam (PF04675) Pfam (PF01068) Pfam (PF04679) Pfam (PF00533) Pfam (PF11411) In PDB	Homo sapiens (human)	DNA ligase IV,Polydeoxyribonucleotide synthase [ATP] 4
11	L, C	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)

Contents of the asymmetric unit

Polymers	Number of chains	22
	Total formula weight	1757468.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1014.4
All*	Total formula weight	1758482.4

*Water molecules are not included.