8EXR

Cryo-EM structure of S. aureus BlaR1 TM and zinc metalloprotease domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A, C	Beta-lactam sensor/signal transducer BlaR1	polymer	602	71269.7	3	UniProt (Q00419) Pfam (PF05569) Pfam (PF00905) UniProt (by SIFTS) (P18357) In PDB	Staphylococcus aureus	Beta-lactamase regulatory sensor-transducer BlaR1,Bla regulator protein blaR1,BlaR1,BlaR1 family beta-lactam sensor/signal transducer,BlaR1 protein,Regulatory protein BlaR1
2	B, A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	B, A	(2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE	non-polymer		747.0	2	Chemie (P6L)
4	B, A	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)

Sequence modifications

B, A, C: 1 - 585 (UniProt: Q00419)

PDB	External Database	Details
Glu 586	-	expression tag
Leu 587	-	expression tag
Ala 588	-	expression tag
Leu 589	-	expression tag
Val 590	-	expression tag
Pro 591	-	expression tag
Arg 592	-	expression tag
Gly 593	-	expression tag
Ser 594	-	expression tag
Ser 595	-	expression tag
Ala 596	-	expression tag
His 597	-	expression tag
His 598	-	expression tag
His 599	-	expression tag
His 600	-	expression tag
His 601	-	expression tag
His 602	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	213809.1
Non-Polymers*	Number of molecules	7
	Total formula weight	1909.7
All*	Total formula weight	215718.8

*Water molecules are not included.