8ETM

Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Diacylglycerol O-acyltransferase 1	polymer	488	55339.1	2	UniProt (O75907) Pfam (PF03062)	Homo sapiens (human)	ACAT-related gene product 1,Acyl-CoA retinol O-fatty-acyltransferase,Retinol O-fatty-acyltransferase,Diglyceride acyltransferase
2	C, D (A, B)	[(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid	non-polymer		551.6	2	Chemie (WTT)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	110678.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1103.1
All*	Total formula weight	111781.4

*Water molecules are not included.