8EJ4
Cryo-EM structure of the active NLRP3 inflammasome disk
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NACHT, LRR and PYD domains-containing protein 3 | polymer | 902 | 102675.6 | 10 | UniProt (Q96P20) Pfam (PF14484) Pfam (PF05729) Pfam (PF17779) Pfam (PF17776) Pfam (PF13516) | Homo sapiens (human) | Angiotensin/vasopressin receptor AII/AVP-like,Caterpiller protein 1.1,CLR1.1,Cold-induced autoinflammatory syndrome 1 protein,Cryopyrin,PYRIN-containing APAF1-like protein 1 |
| 2 | K, L, M, N, O... (K, L, M, N, O...) | Serine/threonine-protein kinase Nek7 | polymer | 278 | 32038.2 | 10 | UniProt (Q8TDX7) Pfam (PF00069) | Homo sapiens (human) | Never in mitosis A-related kinase 7,NimA-related protein kinase 7 |
| 3 | AA, CA, EA, GA, IA... (D, E, F, G, H...) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 10 | Chemie (AGS) | |||
| 4 | BA, DA, FA, HA, JA... (D, E, F, G, H...) | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 1347137.7 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 5475.5 | |
| All* | Total formula weight | 1352613.3 |
