8EI4
Crystal structure of the WWP1 HECT domain in complex with H302, a Helicon Polypeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NEDD4-like E3 ubiquitin-protein ligase WWP1 | polymer | 376 | 44430.9 | 1 | UniProt (Q9H0M0) Pfam (PF00632) | Homo sapiens (human) | Atrophin-1-interacting protein 5,AIP5,HECT-type E3 ubiquitin transferase WWP1,TGIF-interacting ubiquitin ligase 1,Tiul1,WW domain-containing protein 1 |
| 2 | B (B) | H302 | polymer | 19 | 1895.3 | 1 | synthetic construct | ||
| 3 | C, D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 4 | G (B) | N,N'-(1,4-phenylene)diacetamide | non-polymer | 192.2 | 1 | Chemie (WHL) | |||
| 5 | H (A) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 546 - 917 (UniProt: Q9H0M0)
| PDB | External Database | Details |
|---|---|---|
| Gly 542 | - | expression tag |
| Ser 543 | - | expression tag |
| His 544 | - | expression tag |
| Met 545 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46326.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 440.5 | |
| All* | Total formula weight | 46766.6 |
