8E96
Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Glutamate receptor ionotropic, NMDA 1 | polymer | 829 | 93078.3 | 2 | UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1 |
| 2 | B, D (B, D) | Glutamate receptor ionotropic, NMDA 2D | polymer | 887 | 96760.5 | 2 | UniProt (O15399) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Homo sapiens (human) | GluN2D,EB11,Glutamate [NMDA] receptor subunit epsilon-4,N-methyl D-aspartate receptor subtype 2D,NMDAR2D,NR2D |
| 3 | E, I (A, C) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) | |||
| 4 | F, H, J, K, L... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 5 | G, M (B, D) | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) |
Sequence modifications
A, C: 19 - 847 (UniProt: Q05586)
B, D: 28 - 879 (UniProt: O15399)
| PDB | External Database | Details |
|---|---|---|
| Ser 22 | Cys 22 | engineered mutation |
| Asn 844 | Arg 844 | engineered mutation |
| Gly 845 | Arg 845 | engineered mutation |
| Ala 846 | Lys 846 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Trp -7 | - | expression tag |
| Ser -6 | - | expression tag |
| His -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Gly 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Gly 6 | - | expression tag |
| Gly 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Trp 13 | - | expression tag |
| Ser 14 | - | expression tag |
| His 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Gln 17 | - | expression tag |
| Phe 18 | - | expression tag |
| Glu 19 | - | expression tag |
| Lys 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Val 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Arg 26 | - | expression tag |
| Gly 27 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 379677.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1771.6 | |
| All* | Total formula weight | 381449.1 |
