8E50
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycerol-3-phosphate acyltransferase 1, mitochondrial | polymer | 767 | 86919.5 | 1 | UniProt (Q9HCL2) Pfam (PF01553) Pfam (PF19277) | Homo sapiens (human) | GPAT-1 |
| 2 | B (A) | COENZYME A | non-polymer | 767.5 | 1 | Chemie (COA) | |||
| 3 | C (A) | (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate | non-polymer | 410.5 | 1 | Chemie (NKO) |
Sequence modifications
A: 80 - 828 (UniProt: Q9HCL2)
| PDB | External Database | Details |
|---|---|---|
| Met 62 | - | initiating methionine |
| Asp 63 | - | expression tag |
| Tyr 64 | - | expression tag |
| Lys 65 | - | expression tag |
| Asp 66 | - | expression tag |
| Asp 67 | - | expression tag |
| Asp 68 | - | expression tag |
| Asp 69 | - | expression tag |
| Lys 70 | - | expression tag |
| Gly 71 | - | expression tag |
| Ser 72 | - | expression tag |
| Glu 73 | - | expression tag |
| Asn 74 | - | expression tag |
| Leu 75 | - | expression tag |
| Tyr 76 | - | expression tag |
| Phe 77 | - | expression tag |
| Gln 78 | - | expression tag |
| Ser 79 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 86919.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1178.0 | |
| All* | Total formula weight | 88097.5 |
