8E2K

Cryo-EM structure of BIRC6/HtrA2-S306A

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Baculoviral IAP repeat-containing protein 6	polymer	4898	535317.2	2	UniProt (Q9NR09) Pfam (PF00653) Pfam (PF12356) Pfam (PF00179)	Homo sapiens (human)	BIR repeat-containing ubiquitin-conjugating enzyme,BRUCE,RING-type E3 ubiquitin transferase BIRC6,Ubiquitin-conjugating BIR domain enzyme apollon,APOLLON
2	C, D, E (X, Y, Z)	Serine protease HTRA2, mitochondrial	polymer	332	35961.9	3	UniProt (O43464) Pfam (PF13365) Pfam (PF17820)	Homo sapiens (human)	High temperature requirement protein A2,HtrA2,Omi stress-regulated endoprotease,Serine protease 25,Serine proteinase OMI

Sequence modifications

A, B: 1 - 4857 (UniProt: Q9NR09)

PDB	External Database	Details
Met -40	-	expression tag
Gly -39	-	expression tag
Asp -38	-	expression tag
Tyr -37	-	expression tag
Lys -36	-	expression tag
Asp -35	-	expression tag
His -34	-	expression tag
Asp -33	-	expression tag
Gly -32	-	expression tag
Asp -31	-	expression tag
Tyr -30	-	expression tag
Lys -29	-	expression tag
Asp -28	-	expression tag
His -27	-	expression tag
Asp -26	-	expression tag
Ile -25	-	expression tag
Asp -24	-	expression tag
Tyr -23	-	expression tag
Lys -22	-	expression tag
Asp -21	-	expression tag
Asp -20	-	expression tag
Asp -19	-	expression tag
Asp -18	-	expression tag
Lys -17	-	expression tag
Gly -16	-	expression tag
Gly -15	-	expression tag
Gly -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Leu -10	-	expression tag
Glu -9	-	expression tag
Val -8	-	expression tag
Leu -7	-	expression tag
Phe -6	-	expression tag
Gln -5	-	expression tag
Gly -4	-	expression tag
Pro -3	-	expression tag
Ser -2	-	expression tag
Arg -1	-	expression tag
Thr 0	-	expression tag
Val 1332	Leu 1332	conflict

X, Y, Z: 134 - 458 (UniProt: O43464)

PDB	External Database	Details
Met 133	-	initiating methionine
Ala 306	Ser 306	conflict
His 459	-	expression tag
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	1178520.0
All*	Total formula weight	1178520.0

*Water molecules are not included.