8E0F
Human Adenosine Deaminase Acting on dsRNA (ADAR2-RD) bound to dsRNA containing a G-G pair adjacent to the target site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Double-stranded RNA-specific editase 1 | polymer | 488 | 53989.7 | 2 | UniProt (P78563) Pfam (PF00035) Pfam (PF02137) In PDB | Homo sapiens (human) | RNA-editing deaminase 1,RNA-editing enzyme 1,dsRNA adenosine deaminase |
2 | C | RNA (5-R(*GP*CP*UP*CP*GP*CP*GP*AP*UP*GP*CP*GP*(8AZ)P*GP*AP*GP*GP*GP*CP* UP*CP*UP*GP*AP*UP*AP*GP*CP*UP*AP*CP*G)-3) | polymer | 32 | 10355.2 | 1 | Homo sapiens | ||
3 | D | RNA(5-R(*CP*GP*UP*AP*GP*CP*UP*AP*UP*CP*AP*GP*AP*GP*CP*CP*CP*CP*CP*CP*GP*GP*CP*AP*UP*CP*GP*CP*GP*AP*GP*C)-3) | polymer | 32 | 10229.2 | 1 | Homo sapiens | ||
4 | A, B | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) | |||
5 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B: 215 - 701 (UniProt: P78563)
PDB | External Database | Details |
---|---|---|
Gly 214 | - | expression tag |
Gln 488 | Glu 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 128563.8 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1450.9 | |
All* | Total formula weight | 130014.7 |