8DRO

LRRC8A:C conformation 1 (round) LRR focus 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, C	Volume-regulated anion channel subunit LRRC8A,Soluble cytochrome b562	polymer	911	105530.1	2	UniProt (Q80WG5) UniProt (P0ABE7) Pfam (PF12534) Pfam (PF07361) Pfam (PF13855) In PDB	Mus musculus (house mouse)	Leucine-rich repeat-containing protein 8A,Protein ebouriffe,ebo,Cytochrome b-562

Sequence modifications

B, C: -91 - -21 (UniProt: Q80WG5)
B, C: -15 - 89 (UniProt: P0ABE7)

PDB	External Database	Details
Trp -9	Met 29	conflict
Ile 86	His 124	conflict
Leu 90	-	linker

B, C: 91 - 810 (UniProt: Q80WG5)

PDB	External Database	Details
Trp -20	-	linker
Ala -19	-	linker
Ala -18	-	linker
Ser -17	-	linker
Ser -16	-	linker
Ser 811	-	expression tag
Asn 812	-	expression tag
Ser 813	-	expression tag
Leu 814	-	expression tag
Glu 815	-	expression tag
Val 816	-	expression tag
Leu 817	-	expression tag
Phe 818	-	expression tag
Gln 819	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	211060.2
All*	Total formula weight	211060.2

*Water molecules are not included.