8DPV
The crystal structure of Interleukin-11, W147A mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-11 | polymer | 169 | 18158.2 | 1 | UniProt (P20809) Pfam (PF07400) | Homo sapiens (human) | IL-11,Adipogenesis inhibitory factor,AGIF |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 11 - 178 (UniProt: P20809)
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | expression tag |
| Ala 147 | Trp 168 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18158.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 131.5 | |
| All* | Total formula weight | 18289.7 |
