8DIZ
Crystal structure of NavAb I119T as a basis for the human Nav1.7 Inherited Erythromelalgia I234T mutation
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ion transport protein | polymer | 257 | 29777.2 | 1 | UniProt (A8EVM5) Pfam (PF00520) In PDB | Aliarcobacter butzleri RM4018 | |
2 | A | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 5 | Chemie (PX4) |
Sequence modifications
A: 1001 - 1239 (UniProt: A8EVM5)
PDB | External Database | Details |
---|---|---|
Met 983 | - | initiating methionine |
Asp 984 | - | expression tag |
Tyr 985 | - | expression tag |
Lys 986 | - | expression tag |
Asp 987 | - | expression tag |
Asp 988 | - | expression tag |
Asp 989 | - | expression tag |
Asp 990 | - | expression tag |
Lys 991 | - | expression tag |
Gly 992 | - | expression tag |
Ser 993 | - | expression tag |
Leu 994 | - | expression tag |
Val 995 | - | expression tag |
Pro 996 | - | expression tag |
Arg 997 | - | expression tag |
Gly 998 | - | expression tag |
Ser 999 | - | expression tag |
His 1000 | - | expression tag |
Thr 1119 | Ile 119 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29777.2 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 3394.7 | |
All* | Total formula weight | 33171.9 |